Neurosurgery

Christopher M. Loftus, MD, FACS

Professor, Neurosurgery, Lewis Katz School of Medicine at Temple University

About me

Clinical Interests
  • Modeling of intracranial collateral circulation
  • ISUIA - unruptured aneurysm trial
  • IHAST cooperative trial for hypothermia in aneurysm surgery
  • Progesterone therapy for stroke prevention
Research Interests
  • Intracranial collateral circulation
  • Intraoperative hypothermia/aneurysm cooperative trial
  • Extracranial carotid occlusive disease
  • Responses of cerebral blood flow to cerebral revascularization
Education
  • MD, SUNY-Downstate Medical Center, Brooklyn NY
Training
  • Residency, Neurosurgery, The Neurological Institute of New York, Columbia-Presbyterian Medical Center, New York, NY
Board Certification
  • Neurological Surgery
Memberships
  • President, Chicago Neurological Society
  • American Association of Neurological Surgeons
    • Vice President
    • Finance Committee
    • Board of Directors
    • Long Range Planning Committee
    • Professional Conduct Committee
    • Chairman, Publications Committee
    • Chair, International Programs
    • Chairman, International Outreach Committee
    • Medical Director, Kuwait Scholars Project
    • Membership Advisory Committee
  • Chicago Neurological Society
    • Vice President
    • Treasurer
  • World Federation of Neurosurgical Societies Foundation
    • Board of Trustees
    • Assistant Treasurer
  • World Federation of Neurosurgical Societies
    • Treasurer
    • Assistant Treasurer
    • Second Vice President (North America)
  • Scientific Program Chairman, Southern Neurosurgical Society
  • International Advisory Board, Journal of Cerebrovascular Sciences (India)
  • Board of Directors, Inter-Urban Neurosurgical Society
  • The College of Physicians of Philadelphia
  • Honorary Member, Slovak Neurosurgical Society
  • Guest Member, Japan Neurosurgical Society
  • Neurosurgical Society of America
  • American College of Surgeons Advisory Council for Neurological Surgery
Awards and Honors
  • Chicago’s Top Doctors, Chicago Magazine, 2013-2014, 2016
  • The Region’s Top Doctors, Suburban Life Magazine, 2010
  • The Region’s Top Doctors, South Jersey Magazine, 2010
  • Honorary Medical Degree, Pavel Josef Safarik University, Kosice, Slovakia, 2006
  • Philadelphia’s Top Doctors, Philadelphia magazine, 2005-2008, 2010
  • America’s Top Doctors, Castle and Cooke Inc., 2001, 2003
  • Marquis Who’s Who in the South and Southwest, 1998
  • Marquis Who’s Who in America, 1998
  • The Country’s Best Heart Doctors, Good Housekeeping, 1996
  • The Best Doctors in America, 1993, 1996, 1998, 2003-2004, 2015-2016, 2017-2018
  • Outstanding Basic Science Presentation, Residents and Fellows Research Day, University of Iowa College of Medicine, 1992
  • Galbraith Award, Cerebrovascular Research of Year, Congress of Neurological Surgeons Meeting, 1991
  • First Prize, Basic Science Poster Session, AANS Scientific Program, Toronto, Canada, 1988
  • High Distinction in Major Subject, Dartmouth College, 1975

Publications

Selected Publications

Loftus CM, Rozario RA, Prager R, Scott RM:  Solitary osteo-chondroma of T4 with thoracic cord compression.  Surg Neurol 13:355-357, 1980.

Kvam DA, Loftus CM, Copeland B, Quest DO:  Seizures during the immediate postoperative period.  Neurosurgery 12:14-17, 1983.

Loftus CM, Correll JW:  Mediastinal hematoma after carotid endarterectomy.  Surg Neurol 19:171-173, 1983.

Loftus CM, Michelsen CB, Rapoport F, Antunes JL:  Management of plasmacytomas of the spine.  Neuro­surgery 13:30-36, 1983.

Loftus CM, Quest DO:  Current status of carotid en­darterectomy for atheromatous disease.  Neurosurgery 13:718-23, 1983.

Loftus CM, Marquardt MD, Stein BM:  Hemangioblas­toma of the third ventricle.  Neurosurgery 15:67-72, 1984.

Loftus CM, Copeland BR, Carmel PW:  Cystic supra­tentorial gliomas: natural history and evaluation of modes of surgical therapy.  Neurosurgery 17:19-24, 1985.

Solomon RA, Loftus CM, Quest DO, Correll JW:  Inci­dence and etiology of intracerebral hemorrhage fol­lowing carotid endarterectomy.  J Neurosurgery 64:29-34, 1986.

Quest DO, Loftus CM:  Controversies in carotid artery surgery.  Contemporary Neurosurgery 7(25):1-6, 1986.

Loftus CM, Nilaver G, Beinfeld MC, Post KD:  Motilin related immunoreactivity in mammalian adeno­hypophysis.  Neurosurgery 19:201-204, 1986.

Loftus CM, Dyste GN, Reinarz S, Hingtgen W:  Cervical carotid dissection following carotid endarterectomy: A complication of indwelling shunt?  Neurosurgery 19:441-445, 1986.

Biller J, Loftus CM, Moore SA, Schelper R, Danks KR, Cornell SH:  Isolated central nervous system agilities first presenting as spontaneous intracranial hemorrhage.  Neurosurgery 20:310-315, 1987.

Quest DO, Loftus CM:  Controversial aspects of carotid artery surgery.  Surgical Rounds 10: 53-62, 1987.

Loftus CM, Quest DO:  Technical controversies in carotid artery surgery.  Neurosurgery 20:490-495, 1987.

Loftus CM, Biller J, Hart MN, Cornell SH, Hiratzka LF:  Management of radiation induced accelerated carotid atherosclerosis.  Arch Neurol 44:711-714, 1987.

Loftus CM, Bernstein DD, Starr J, Yamada T, Wegrzynowicz E, Kosher T:  Measurement of rCBF and somatosensory evoked potentials in a canine model of hemispheric ischemia.  Neurosurgery: 21:503-508, 1987.

Loftus CM, Salved JA, Bernstein DD, Hitchon PW, Kosier T:  Effects of pre-existing bypass graft on rCBF and Seep’s following acute canine stroke.  J Neurosurgery 67:421-427, 1987.

Miller BV, Loftus CM, Hiratzka LF, Laughlin DE:  Technical note: In vitro evaluation of an in-line Doppler flow metering system for carotid artery shunt.  Neurosurgery 22:608-612, 1988.

Loftus CM:  Carotid endarterectomy: Current indications for elective and emergency surgery.  Postgrad Med 82(5):241-248, 1987.

Loftus CM, Biller J, Godowsky JC, Adams HP, Yamada T, Edwards PS: Carotid endarterectomy in symptomatic elderly patients.  Neurosurgery 22:676-680, 1988.

Beck DW, Adams HP, Flamm ES, Godowsky JC, Loftus CM: The combination of aminocaproic acid and nicardipine in the treatment of aneurysmal subarachnoid hemorrhage. Stroke 19:63-67, 1988.

Flamm ES, Adams HP, Beck DW, Marler J, Walker MD, Pinto RS, Godowsky JC, Loftus CM, Biller J, Boarini DJ, O'Dell C, Banwart K, Kongable G: A dose escalation study of intravenous nicardipine in patients with recent aneurysmal subarachnoid hemorrhage. J Neurosurgery 68:393-400, 1988.

Silvidi JA, Loftus CM, Bernstein DD, Kosier T:  Sequential measurement of somatosensory evoked potentials in a canine model of hemispheric ischemia.  Neurological Research 10:179-183, 1988.

Loftus CM, Biller J: Modern management of carotid atheromatosis.  Neurocirugia 3:62-72, 1989.

Loftus CM: Technique of carotid endarterectomy.  Contemp Neurosurgery 10:(5) 1-6, 1988.

Olson JJ, Loftus CM, Hitchon PW:  Metastatic pheochromocytoma of the cervical spine.  Spine 14: 349-51, 1989.

Becker JA, Loftus CM, Detailer KN, Salved JA, Bernstein DD:  Hypertensive manipulation and in-line Doppler flow monitoring of blood flow through carotid artery shunts in the goat.  Surgical Forum XXXIX:489-493, 1988.

Mattos MA, Shamma AR, Rossi N, Meng R, Godowsky JG, Loftus CM:  Recurrent carotid stenosis: Is duplex follow-up cost effective in the first postoperative year?  Am J Surg 156:91-95, 1988.

Loftus CM, Salved JA, Becker JA, Miller BV, Bernstein DD:  Correlation of experimental rCBF determinations in goats with flow measurements from a Doppler-modified carotid artery shunt.  J Ultrasound Med: 8:7-13, 1989.

Loftus CM, Silvidi JA, Bernstein DD, Kosher T:  Effects of hypercapnia on rCBF following prophylactic and delayed experimental STA-MCA bypass.  Surg Neurol 31:183-9, 1989.

Biller J, Bruno A, Adams HP, Godowsky JC, Loftus CM, Mitchell VL, Banwart KJ:  A randomized trial of aspirin or heparin in hospitalized patients with recent transient ischemic attacks.  Stroke 20: 441-447, 1989.

Loftus CM, Detwiler KN, Zhou JG, Silvidi JA, Bernstein DD:  Cerebral autoregulation following prophylactic and delayed experimental STA-MCA bypass.  Acta Neurochir 101:75-79, 1989.

Zhou JG, Todd MM, Warner DS, Loftus CM: The effects of nitrous oxide on electroencephalographically-determined ischemic thresholds in the rat.  J Neurosurgery Anesth 1:103-109, 1989.

Osenbach RK, Loftus CM, Menezes AH, Biller J, Stannous R, Yuh WTC:  Management of intraventricular hemorrhage secondary to ruptured arteriovenous malformation in a child with von Will brand’s disease.  J Neurol Neurosurgery Psychiat 52:1452-1454, 1989.

Detailer KN, Loftus CM, Menezes AH, Godowsky JC: Management of cervical spine injuries in patients with ankylosing spondylitis.  J Neurosurg 72:210-215, 1990.

Loftus CM, Greene GM, Detailer KN, Baumbach GL, Harrison DG, Heistad DD:  Studies of collateral perfusion to canine middle cerebral artery territory.  Am J Physiol. 259 (Heart Circ. Physiol.28):H560-H566, 1990.

Greene GG, Hart MN, Poor Jr. MM, Loftus CM:  Carcinoma metastatic to a cerebellar vascular malformation: case report.  Neurosurgery 26:1054-1057, 1990.

Loftus CM: Carotid artery disease.  Neurosurgical Consultations, Volume 1, Issue 20, 1990.

Struck LK, Biller J, Bruno A. Neiman RF, Loftus CM, Yuh WTC, Marsh EE, Adams HP: Superior cerebellar artery territory infarction. Cerebrovascular Diseases 1:71-75, 1991.

Loftus CM:  Diagnosis and management of nontraumatic subarachnoid hemorrhage in elderly patients. Clin Geriatr Med 7(3):569-582 1991.

Loftus CM: Enraptured intracranial aneurysms.  Neurosurgical Consultations 3:1992.

Greene GM, Mahoney MG, Detwiler KN, Heisted DD, Loftus CM:  Stem pressure at the origin of intracranial collateral vessels.  Am J Physiology 262 (Heart Circ. Physiol. 31):H1294-1297,1992.

Mahoney MG, Sawin PD, Heistad DD, Loftus CM:  Pressure flow relationships in canine collateral-dependent cerebrum.  Stroke 23:988-994, 1992.

Muhonen MG, Greene GM, Heistad DD, Loftus CM: Mechanism of cerebral vascular "steal" phenomenon during hypercarbia and seizures.  Stroke 23:139, 1992.

Loftus CM: Current diagnosis and management of subarachnoid hemorrhage of all causes.  Neurosurgery Quarterly 2(1):44-58, 1992.

Loftus CM: Concomitant carotid and coronary disease, Patient Care, January 15, 1992, Volume 26, No. 1.

Kline JN, Royals TJ, Galvin JR, Loftus CM, Hunter JH: Pulmonary embolization and infarction: An iatrogenic complication of transcatheter embolization of a cerebral arteriovenous malformation with polyvinyl alcohol sponge. Chest 103:1293-1295, 1993.

Mahoney MG, Greene GM, Heisted DD, Loftus CM: Mechanism of redistribution of cerebral blood flow during hypercarbia and seizures.  Am J Physiol (Heart Circ Physiology 35):H2074-2081, 1994.

Loftus CM: Surgical management options to prevent ischemic stroke.  Neurosurgery Quarterly 4(1):1-38, 1994.

Loftus CM:  Perioperative management of spontaneous primary subarachnoid hemorrhage.  Contemp Neurosurgery 16: #22, 1994.

Loftus CM, Biller J:  Acute cerebral ischemia.  Pathophysiology and medical treatment.  Contemp Neurosurg 16: #25, 1994.

Loftus CM, Biller J:  Acute cerebral ischemia.  Surgical management.  Contemp Neurosurgery 16: #26, 1994.

Mahoney MG, Faraci F, Heisted DD, Loftus CM: Augmentation of blood flow through cerebral collaterals by inhibition of nitric oxide synthase.  Journal of Cerebral Blood Flow and Metabolism: 14:701-714, 1994.

Loftus CM, Biller J:  Manejo moderno de la ateromatosis carotidea.  Tendencies en Medicinal (Uruguay) 4: 25-38, 1994.

Loftus CM, Hopkins LN:  Paradoxical indications for carotid endarterectomy.  Neurosurgery 36:99-100, 1995.

Loftus CM, Quest DO: Technical issues in carotid surgery 1995.  Neurosurgery 36:629-647, 1995. 

Sawin P, Loftus CM:  Posterior interosseous nerve palsy following brachiocephalic arteriovenous fistula construction: Report of two cases.  Neurosurgery 37:537-540, 1995.

Mahoney MG, Loftus CM, Heisted DD:  Effects of adenosine and 2-Chloroadenosine on cerebral collateral vessels.  J Cereb Blood Flow Metal 15:1075-1081, 1995.

Biller J, Loftus CM:  Intracerebral hemorrhage.  Topics in Stroke Rehabilitation 3:13-27, 1996.

Loftus CM:  Carotid endarterectomy: conventional and microsurgical techniques.  Congress of Neurological Surgeons, Video Perspectives in Neurological Surgery Series 1996.

Sawin PD, Loftus CM:  Spontaneous subarachnoid hemorrhage: Diagnostic and therapeutic considerations for the primary care physician.  Am Fam Phys 55:145-156, 1997.

Robertson SC, Mazzochi C, Loftus CM:  Effects of serotonin (5-HT) and selective 5-HT receptor antagonists on regional cerebral blood flow after middle cerebral artery occlusion.  Surgical Forum XLVII:561-563, 1996.

Rubin MD, Sato Y, Crosby DC, Traynelis VC, Loftus CM, Follett KA, Sawin PD, Ogura Y, Katada Y:  In vivo dissection of cerebral aneurysms using CT angiography. Int J Neuroradiol 2 (6):510-521, 1996.

Loftus CM:  Technical fundamentals, monitoring, and shunt use during carotid endarterectomy.  Techniques in Neurosurgery 3: 16-24, 1997.

Hath JA, Piper JG, Loftus CM:  Hypoplastic internal carotid artery mimicking a classic angiographic "string sign".  J Neurosurgery 86:567-570, 1997.

Robertson SC, Bara M, Girds JS, Loftus CM:  Effects of glibenclamide on regional cerebral blood flow.  Surgical Forum XLVIII:  536-539, 1997.

Muhonen MG, Robertson SC, Girds JS, Loftus CM:  Effects of serotonin on cerebral circulation following middle cerebral artery occlusion. J Neurosurgery 87:301-306, 1997.

Robertson SC, Witten NM, Beer BJ, Loftus CM:  Pre and post-ischemic effects of the NMDA receptor antagonist discipline maleate (MK-801) on collateral cerebral blood flow.  J Neurosurgery 87:927-933, 1997.

Loftus CM:  Technical aspects of carotid endarterectomy with hemashield patch graft.  Neurologia medico-chirurgia (Tokyo) 37:  805-818, 1997.

Loftus CM:  Current indications for carotid endarterectomy.  Neurologia medico-chirurgia (Tokyo) 38:  268-274 1998..

Garell PC, Noh D, Loftus CM, Hitchon PW, Howard MA:  Single-handed variable stiffness introducer for catheters.  J Clin Engineering 23: 1-4, 1997.

Robertson SC, Loftus CM:  Effect of N-methyl-d-aspartate and inhibition of neuronal nitric oxide on collateral cerebral blood flow after middle cerebral occlusion. Neurosurgery 42: 117-124, 1998.

Batman MA, Katzen BT, Whisnant J, Brant-Zawadzki M, Broderick JP, Furan AJ, Hershey LA, Howard V, Kuntz R, Loftus CM, Pearce W, Roberts A, Roubin G:  Carotid stenting and angioplasty. A statement for healthcare professionals from the councils on cardiovascular radiology, stroke, cardio-thoracic and vascular surgery, epidemiology and prevention, and clinical cardiology, American Heart Association.  Circulation 97:121-123, 1998.

Batman MA, Katzen BT, Whisnant J, Brant-Zawadzki M, Broderick JP, Furan AJ, Hershey LA, Howard V, Kuntz R, Loftus CM, Pearce W, Roberts A, Roubin G:  Carotid stenting and angioplasty. A statement for healthcare professionals from the councils on cardiovascular radiology, stroke, cardio-thoracic and vascular surgery, epidemiology and prevention, and clinical cardiology, American Heart Association.  J Vasc Interv Radiol 9:3-5, 1998.

Wellman BJ, Loftus CM:  Bilateral (mirror-image) aneurysms at the origin of the posterior inferior cerebellar artery.  Neurosurgery 42:938-940, 1998.

Wellman BJ, Loftus CM, Noh D, Barnhart WH, Howard MH III:  A combined surgical-endovascular device concept for giant aneurysm neck occlusion.  Neurosurgery 42:1364-1369, 1998.

Robertson SC, Brown P, Loftus CM:  Effects of etomidate administration on cerebral collateral flow. Neurosurgery 43:317-324, 1998.

Wellman BJ, Loftus CM, Kresowik TF, Todd MM, Granner MA:  The differences in electroencephalographic changes in local versus general anesthesia carotid endarterectomy patients.  Neurosurgery 43:769-775, 1998.

Garell PC, Mirsky R, Noh MD, Loftus CM, Hitchon PW, Grady MS, Dacey RG, Howard MA:  Posterior ventricular catheter burr-hole localizer.  J Neurosurg 89:157-160, 1998.

Hindman BJ, Todd MM, Gelb AW, Loftus CM, Craen RA, Schubert A, Mahla M, Torner JC:  Mild hypothermia as a protective therapy during intracranial aneurysm surgery:  A randomized prospective pilot trial. Neurosurgery 44:23-33, 1999.

Loftus CM:  Surgical management of extracranial carotid artery disease.  Surgery for Cerebral Stroke (Japan) 27:7-13,1999.

Wetjen NM, Garell PC, Stence NV, Loftus CM:  Moyamoya disease in the Mid-Western United States.  Neurosurg Focus 5 (5):Article 1, 1998.

Brennan JJ, Loftus CM: Carotid Endarterectomy:  Current indications for surgery. Neurosurgical Focus 5 (6):Article 1, 1998.

Loftus CM: Design characteristics and clinical of a newly designed carotid artery shunt. Neurological Research 22:443-448, 2000.

Kumon Y, Kim B, Stevens A, Tompkins P, Loftus CM:  Post-ischemic administration of progesterone is neuroprotective in spontaneously hypertensive rats with focal cerebral ischemia.  J Neurosurg 92:848-852, 2000.

Stafira JS, Yuh, WTC, Sonnad JR, Huard DR, Acker RE, Nguyen DL, Maley JE, Ramji FG, Li W, Loftus CM:  Qualitative assessment of cervical spinal stenosis: Observer variation on CT and MR images. AJNR 24:766-769, 2003..

Surdell DL, Bhattacharjee S, Loftus CM:  Pros, cons, and current indications of open craniotomy vs. gamma knife in the treatment of arteriovenous malformations and the role of endovascular embolization. Neurological Research 24:1-7, 2002.

Pack JR, Yuh WTC, Sonnad JR, Maley JE, Petropoulou K, Wegner KF, Loftus CM, Mayr NA, Whitehead DP, and Maier GJ,   Request Form History, Clinical Indication, and Yield of Brain MR Studies, Journal of Magnetic Resonance Imaging 20 (2):228-234, 2004..

Loftus CM: High risk carotid endarterectomy and high-risk carotid surgery: Is surgery or stenting the best choice? International Congress Series 1247:319-326, December 2002.

Snell BE, Loftus CM: Carotid endarterectomy Part 1: Indications and preoperative planning.  Contemp Neurosurg 25(20):1-6, 2003.

Snell BE, Loftus CM:  Carotid endarterectomy Part II: Surgical technique and management of concurrent vascular diseases. Contemp Neurosurg 25 (21):1-6, 2003.

Wienecke RJ, Loftus CM:  Multilevel cervical discectomy and fusion for cervical spondylitic myelopathy.  Seminars in Neurosurgery 14(1):15-20, 2003.

Baron EM, Levene HB, Heller JE, Jallo JI, Loftus CM, Dominique DA: Neuroendoscopy for spinal disorders: a brief review.  Neurosurg Focus 19 (6):E5, 2005.

Baron EM, Loftus CM, Vaccaro AR, Dominique DA: Anterior Cervical Approach to the Subaxial Cervical Spine in children. Neurosurgical Focus 20 (2): E4, 2006.

Baron EM, Baty DE, Loftus CM:. The Timing of Cartotid Endarterectomy Post Stroke. Neurol Clin. 2006 Nov;24(4):669-80.

Tyagi R, Donaldson K, Loftus CM, Jallo J:  Hypertonic saline: a clinical review.  Neurosurg Review 30 (4): 277-290,  2007.

Dominique D, Donaldson K, Sumas M, Baron E, Jallo J, Laske D, Loftus CM:  Vertebral body replacement with the VBR cage in the setting of metastatic spinal disease.  International Proceedings of the EANS 2007, Bologna,  Medimond S.r.l., 2007.

Levene, HB, Zhang M, Erb CJ, Jallo JI, Loftus CM, Tuma RF: Method to perform IV injections on mice using the facial vein. J Neurosci Methods, 2007. 164(2): p. 304-7.

Levene HB, Mohamed FB,  Faro SH, Seshardri AB, Loftus CM, Tuma RF, Jallo JI: Small Mammal MRI Imaging in Spinal Cord Injury:  A Novel Practical Technique for using a 1.5 Tesla MRI. J Neurosci Methods 172:2(245-9)2008 Jul 30.

Baron EM, Baty DE, Loftus CM:. The Timing of Cartotid Endarterectomy Post Stroke. Neurosurg Clin North Am 2008 (in press).

Levene HB, Elliott M, Gaughan JP, Loftus CM, Tuma RF, Jallo JI: A Murine Model of Hypertonic Saline as a Treatment for Acute Spinal Cord Injury: Effects on Autonomic Outcome. J Neurosurg (Spine): in press 2008.

Dominique D, Donaldson K, Sumas M, Baron E, Jallo J, Laske D, Loftus CM:  Vertebral body replacement with the VBR cage in the setting of metastatic spinal disease.  International Proceedings of the EANS 2007, Bologna,  Medimond S.r.l., 2007.

Levene, HB, Zhang M, Erb CJ, Jallo JI, Loftus CM, Tuma RF: Method to perform IV injections on mice using the facial vein. J Neurosci Methods, 2007. 164(2): p. 304-7.

Levene HB, Mohamed FB, Faro SH, Seshadri AB, Loftus CM, Tuma RF, Jallo JI, Small mammal MRI imaging in spinal cord injury: a novel practical technique for using a 1.5 T MRI. J Neurosci Methods 172:2(245-9)2008 Jul 30.

Baron EM, Baty DE, Loftus CM:. The Timing of Cartotid Endarterectomy Post Stroke. Neurosurg Clin North Am 2008 (in press).

Levene HB, Elliott M, Gaughan JP, Loftus CM, Tuma RF, Jallo JI: A Murine Model of Hypertonic Saline as a Treatment for Acute Spinal Cord Injury: Effects on Autonomic Outcome. J Neurosurg Spine 14:131–138, 201.

Ackerman P, Loftus CM: Should we adopt micro-Inter-intimal dissection a novel and worthwhile advance in carotid surgery technique, and will it prevent restenosis and early neurological deficits? World Neurosurgery 2013 (in press).

Loftus CM: Tricks, Science and Superiority in CEA.  Perspectives Comment. World Neurosurgery 2015 (in press).

Chaudhry F, Biller J, Braca J, Loftus CM. Armored brain. Arquivos De Neuro-Psiquitria. (in press 2013).

Hayward DM, Johans SJ, Rosenblum JD, Loftus CM, Ashley WW:  Balloon-Occlusion catheter Onyx embolization of a spinal dural arteriovenous fistula presenting with subarachnoid hemorrhage in a pediatric patient.  J Stroke Cerebrovasc Diseases 25 (4) 2016: e46-e49.

Loftus CM, Iqbal OQ: Antiplatelet therapy, anticoagulation and neurosurgical emergencies. J Cerebrovasc Sciences (India) 2016 (in press).

Books and/or Chapters
Loftus CM, Silvidi JA, Bernstein DD,  Effect of pre-existing STA-MCA bypass on rCBF and SSEP's following acute stroke in dogs.  In Suzuki J (ed.):  Advances in Surgery for Cerebral Stroke. Tokyo, Springer-Verlag, 1988,  pp.615-619.

Biller J, Loftus CM: Hemorrhagic stroke.  In Roman GC (ed.): Tropical Neurology. New York, CRC Publishing Company, 1988.

Loftus CM, Biller J:  Management of multiple brain abscesses.  In Wilkins RH, Rengachary SS (eds.): Neurosurgery Update II. New York, McGraw-Hill, 1991 pp. 282-285.

Post KD, Loftus CM, Lustgarten J:  Pituitary tumors in the aged.  In Sammi M (ed.): Surgery of the Sellar Region and Paranasal Sinuses. Berlin, Springer-Verlag 1989.

Loftus CM: Diagnosis and management of non-traumatic subarachnoid hemorrhage in elderly patients.  In Biller J (ed.): Clinics in Geriatric Medicine, 7:569-582, 1991.

Loftus CM: Surgical Management options to prevent ischemic stroke.  In Adams, HP (ed.): Handbook of Cerebrovascular Diseases, Marcel Dekker, Inc. 1991.

Loftus CM: Indications for surgery in extracranial carotid disease.  In Awad IA (ed.): Cerebrovascular Occlusive Disease and Brain Ischemia. Neurosurgery Topics Series, AANS Publications Committee, 1992, pp. 155-165.

Ryken TC, Loftus CM: Anterior communicating artery aneurysms.  In Rengachary SS and Wilkins RH (eds.): Neurosurgical Operative Atlas, Williams and Wilkins, Baltimore, 1992.

Osenbach RK, Loftus CM:  Diagnosis and management of brain abscess.  Neurosurgery Clinics of North America, 3(2):403-420, 1992.

Ryken TC, Loftus CM: Surgical management of cerebral abscess.  In Wilkins R (ed.): Neurosurgical Operative Atlas, Williams and Wilkins, Baltimore 1993.

Muhonen MG, Heistad DD, Loftus CM: Microcirculatory consequences of collateral circulation during arterial occlusion: implications for a penumbra, in Tomita M, (ed.): Symposium on  Microcirculatory Stasis in the Brain.  Elsevier, 1993 pp. 241-248.

Loftus CM: Monitoring during extracranial carotid reconstruction.  In Loftus CM, Traynelis VC (eds.): Intraoperative Monitoring Techniques in  Neurosurgery.  McGraw-Hill, New York, 1994 pp. 3 - 8.

Loftus CM: Microvascular Doppler in cerebrovascular surgery.  In Loftus CM, Traynelis VC (eds.): Intraoperative Monitoring Techniques in Neurosurgery.  New York,  McGraw-Hill, 1994,  pp. 73-76.

Loftus CM (ed.): Clinical Neurosurgery Volume 41.   Baltimore,  Williams and Wilkins, 1994.

Loftus CM (ed.): Neurosurgical Emergencies Volume 1, Neurosurgery Topic Series, AANS Publications Committee, 1994.

Loftus CM (ed.): Neurosurgical Emergencies Volume 2, Neurosurgery Topic Series, AANS Publications Committee, 1994.

Loftus CM, Biller J: Brain Abscess.  In Rengachary SS and Wilkins RH (eds.): Principles of Neurosurgery, Gower Medical Publishing, 1994, pp. 24.1 - 24.9.

Loftus CM, Traynelis VC (eds.): Intraoperative Monitoring Techniques in Neurosurgery.  New York,  McGraw-Hill, 1994.

Loftus CM:  Carotid Endarterectomy:  Principles and Technique.  St. Louis, Quality Medical Publishing, 1995.

Loftus CM, Biller J: Acute medical and surgical management of stroke.  In Tindall G, Cooper PR, Barrow DL (eds.): The Practice of Neurosurgery,  Baltimore,  Williams and Wilkins, 1995.

Loftus CM (ed.): Clinical Neurosurgery Volume 42.  Baltimore,  Williams and Wilkins, 1995.

Loftus CM (ed.):  Neurosurgical Aspects of Pregnancy.  Neurosurgery Topic Series, AANS Publications Committee, 1995.

Beer SJ, Loftus CM:  Back pain in pregnancy.  In Loftus CM (ed.):  Neurosurgical Aspects of Pregnancy.  Neurosurgery Topic Series, AANS Publications Committee, 1995.

Loftus CM, Osenbach R, Biller J: Diagnosis and management of brain abscess.  In Wilkins RH (ed.): Neurosurgery (Second Edition).  New York,  McGraw-Hill, 1996.

Loftus CM:  Management of intracerebellar hematomas and infarcts.  In Welch KMA, Caplan L, Reis D, Weir B, Siesjö B (eds.):  Primer on Cerebrovascular Diseases.  New York,  Academic Press, 1996 (pp.503-508).

Loftus CM:  Carotid endarterectomy: The asymptomatic carotid.  In Batjer HH (ed.):  Cerebrovascular Disease.  New York,  Lippincott-Raven, 1996, pp.409-420.

Loftus CM (ed.): Clinical Neurosurgery Volume 43.  Baltimore,  Williams and Wilkins, 1996.

Grossman RG, Loftus CM (eds.):  Principles of Neurosurgery, 2nd edition.  New York,  Lippincott-Raven 1999.

Osenbach RK, Loftus CM:  Central nervous system infections.  In Grossman RG, Loftus CM (eds.):  Principles of Neurosurgery, 2nd edition.  New York,  Lippincott-Raven, 1999.

Fleck JD, Biller J, Loftus CM:  Medical and surgical management of stroke and extracranial carotid artery disease.  In Grossman RG, Loftus CM (eds.):  Principles of Neurosurgery, 2nd edition.  New York,  Lippincott-Raven, 1999.

Loftus CM:  Carotid Endarterectomy (Guest Editor).  Techniques in Neurosurgery 3:1-84, 1997.

Loftus CM:  Acute surgical therapeutic interventions in stroke patients.  In Selman WR, Lust WD (eds.):  Brain Attack: The Acute Pathophysiology of Cerebral Ischemia and Its Emergent Treatment.  Neurosurgery Clinics of North America 8: 227-236, 1997.

Loftus CM:  Carotid Endarterectomy: How the Operation is Done.  Clinical Neurosurgery 44: 243-265, 1997.

Loftus CM:  Anesthesia for Carotid Endarterectomy: General vs. Local?  In Bederson JB, Tuhrim S (eds.): Treatment of Carotid Disease:  A Practitioner’s Manual.  Park Ridge Il, AANS Publications 1998, pp. 181-190.

Loftus CM:  Occlusive cerebrovascular disease in geriatric patients. In Selman WR (ed.):  Geriatric Neurosurgery. Park Ridge Il, AANS Publications, 1999,  pp. 103-111.

Loftus CM, Robertson SC:  Technique of carotid endarterectomy with special emphasis on Hemashield patch graft technique.  In:  Proceedings of the 11th International Congress of Neurological Surgery, Monduzzi Editore, Bologna Italy, 1997, pp.1049-1057.

Robertson SC, Loftus CM:  The role of neuronal nitric oxide (NO) in collateral and normal regional cerebral blood flow (rCBF).  Clinical Neurology and Neurosurgery 99: Supplement 1, 141, 1997.

Loftus CM:  Current indications for carotid endarterectomy.  In Salcman M, Awad IA (eds.):  Current Techniques in Neurosurgery.  Philadelphia, Current Science Inc, 1997, pp.139-151.

Loftus CM:  Carotid stenosis:  The case for endarterectomy.  Clinical Neurosurgery 45: 256-259, 1999.

Loftus CM: Preface. In Osenbach RK, Zeidman S:  Infections in Neurological Surgery: Diagnosis and Management.  New York, Lippincott, Williams and Wilkins, 1999.

Traynelis VC, Andrews BT, Awad IA, Batjer HH, Belzberg A, Leibrock L, Couldwell W, Follett K, Friedman A, Loftus CM, Maniker A, Mapstone T, Pollock BE, Schochet SS Jr., Valadka A, Wolfla C:  Resident curriculum guidelines for neurosurgery. Congress of Neurological Surgeons Education Committee. Clinical Neurosurgery 47:589-681, 2000.

Loftus CM, Kresowik TF: Anatomic basis and technique of carotid endarterectomy.  In Loftus CM, Kresowik TF (eds.):  Carotid Artery Surgery.  New York, Thieme Medical Publishers, 2000, pp.245-256.

Loftus CM: Propagating intraluminal carotid thrombus - surgery or anticoagulation?  In Loftus CM, Kresowik TF (eds.):  Carotid Artery Surgery.  New York, Thieme Medical Publishers, 2000, pp.321-328.

Loftus CM:  Surgical anatomy, technique, and indications for carotid endarterectomy.  In Matsuno H (ed.):  Proceedings of the 12th Microsurgical Anatomy Seminar Program, Tokyo, SciMed Publications,  1998.

Honeycutt JH, Loftus CM:  Carotid stump syndromes and external revascularization.  In Loftus CM, Kresowik TF (eds.):  Carotid Artery Surgery.  New York, Thieme Medical Publishers, 2000, pp.315-320.

Loftus CM:  Overview of shunt controversy.  In Loftus CM, Kresowik TF (eds.):  Carotid Artery Surgery.  New York, Thieme Medical Publishers, 2000, pp.409-420.

Loftus CM, Kresowik TF (eds.):  Carotid Artery Surgery.  New York, Thieme Medical Publishers, 2000.

Honeycutt JH, Loftus CM:  Surgical management of extracranial carotid stenosis.  In Schmidek HH and Sweet WH (eds.):  Operative Neurosurgical Techniques.  Philadelphia, W.B. Saunders, 2000, pp. 1067-1079.

Min WD, Loftus CM:  The history of carotid surgery.  In Dagi TF (ed.):  The History of Neurosurgery.  Neurosurgical Clinics of North America, W.B. Saunders, 2001, pp. 167-172.

Grossman RG, Loftus CM (eds.):  Principles of Neurosurgery, 2nd edition.  (Chinese Translation). New York,  Lippincott-Raven 2002.

Fleck JD, Biller J, Loftus CM:  Carotid occlusive disease – Natural history and medical management.  In Winn HR (ed.):  Youmans’ Neurological Surgery, Sixth Edition, Philadelphia, W.B. Saunders 2003, pp. 1613-1620.

Honeycutt JH, Loftus CM:  Carotid endarterectomy: General principles and surgical technique.  Neurosurgical Clinics of North America 11 (2):279-297, 2000.

Loftus CM: Extracranial carotid lesions which should be managed with angioplasty and stenting.  Clinical Neurosurgery 47:249-256, 2000.

Ikezaki K, Loftus CM (eds.):  MoyaMoya Disease.  Chicago, American Association of Neurological Surgeons Press, 2001.

Wetjen, NM, Loftus CM:  Midwest and American surgical experience with MoyaMoya disease.  In Ikezaki K, Loftus CM (eds.):  MoyaMoya Disease.  Chicago, American Association of Neurological Surgeons Press, 2001, pp. 107-118.

Snell BE, Loftus CM: Surgical treatment of distal anterior cerebral artery aneurysms.  In Batjer HH, Loftus CM (eds.):  Textbook of Neurological Surgery.  Philadelphia, Lippincott, Wiliams, and Wilkins, 2003, pp. 2397-2401.

Batjer HH, Loftus CM (eds.):  Textbook of Neurological Surgery.  Philadelphia, Lippincott, Wiliams, and Wilkins, 2003.

Snell BE, Wienecke R, Loftus CM: Surgical Management of Extracranial Vascular Occlusive Disease.  In Lawton M, Gress D, Higashida R (eds.), Controversies in Neurological Surgery: Neurovascular Diseases.  New York, Thieme, 2006, pp. 174-182.

Loftus CM, Stanfield MR:  Carotid Endarterectomy. In Batjer HH, Loftus CM (eds.):  Textbook of Neurological Surgery.  Philadelphia, Lippincott, Williams, and Wilkins, 2003, pp. 2259-2269.

Wienecke, R, Loftus CM:  MoyaMoya Disease.  In Rengachary S, Maciunas R, Wilkins RH:  Neurosurgery (3rd edition), (in press 2006).

Snell BE, Loftus CM:  Extracranial carotid artery atherosclerosis: Carotid endarterectomy. In Rengachary S, Maciunas R, Wilkins RH:  Neurosurgery (3rd edition), (in press 2006).

Bhattacharjee S, Loftus CM:  Carotid endarterectomy: Neurosurgical Perspective. In Sekhar L, Fessler R (eds.): Atlas of Neurosurgical Techniques: Brain.  New York, Thieme Medical Publishers, 2006, pp.330-339.

Loftus CM:  High risk carotid endarterectomy and high-risk carotid surgery: is surgery or stenting the best choice?  In Watanabe K (ed.):  Developments in Neuroscience. Amsterdam, Excerpta Medica International Congress Series 1247, Elsevier, 2002, pp. 319-326.

Snell B, Loftus CM: Cervical Carotid Revascularization: Indications from a surgical perspective.  In Guterman L, Hopkins LN: Neurosurg Clin N Am 16 (2005) 257-258.

Snell B, Honeycutt JH, Loftus CM: Surgical Management of Extracranial Carotid Artery Disease. In Schmidek HH, Roberts DW (eds.): Operative Neurosurgical Techniques, 5th edition.  Philadelphia, Saunders/Elsevier, 2004, pp. 1041-1053

Wienecke RJ, Loftus CM: A Case of Carotid Artery Reconstruction.  In Kobayashi S (ed.):  Neurosurgery of Complex Vascular Lesions and Tumors.  New York, Thieme Medical Publishers, 2005, pp.120-121.

Loftus CM:  Commentary on Okada Y, Hori T: A Case of Right Carotid Endarterectomy and Axilloaxillary Bypass for Symptomatic Carotid Stenosis with Innominate Artery Occlusion. In Kobayashi S (ed.):  Neurosurgery of Complex Vascular Lesions and Tumors.  New York, Thieme Medical Publishers, 2005, pp.115-120.

Loftus CM:  Carotid Artery Surgery: Principles and Technique. 2nd edition.  New York, Informa Publishing 2006.

Baron EM, Bhattacharjee S, Wienecke R., Loftus CM:  Arteriovenous Malformations in Pregnancy in Steig, PS. Batjer, HH, Samson D: Intracranial Arteriovenous Malformations.  New York, Informa Healthcare, 2007.

Jacka M, Baty DE, Baron EM, Loftus CM, Findlay JM. Carotid Microndarterectomy. in Macdonald, RL. Neurosurgical Operative Atlas, 2nd Edition, Thieme Medical Publishing, New York, 2008 (pp.223-230).

Baty DE, Baron EM, Loftus CM: Brain Abscesses. In Goodrich JT (ed.): Neurosurgical Operative Atlas: Pediatric Neurosurgery, 2nd Edition.  New York, Thieme Medical Publishers, 2008, pp. 157-165.

Baron EM, Baty DE, Loftus CM:  Carotid Endarterectomy.  In Connolly ES, McKhann GM, Huang J, Choudri RF and Mocco J (eds.).  Fundamentals of Operative Techniques in Neurosurgery. Thieme Medical Publishing, New York, 2007, pp.161-167.

Levene HB, Erb CJ, Gaughan JP, Loftus CM, Tuma RF, Jallo JI, Hypertonic saline as a treatment for acute spinal cord injury: effects on somatic and autonomic outcomes as observed in a mouse model. Clin Neurosurg 54:(213-9)2007 


Baty DE, Zhang M, Li H, Erb CJ, Adler MW, Ganea D, Loftus CM, Jallo JI, Tuma RF, Cannabinoid CB2 receptor activation attenuates motor and autonomic function deficits in a mouse model of spinal cord injury. Clin Neurosurg 55:(172-7)2008.

Loftus CM (ed.):  Neurosurgical Emergencies, 2nd edition.  New York, Thieme Medical Publishers, 2008.

Jallo JI, Loftus CM (eds.):  Neurotrauma and Critical Care of the Brain.  New York, Thieme Medical Publishing 2009.

Heller JE, Baty DE, Zhang M, Li H, Adler M, Ganea D, Gaughan J, Loftus CM, Jallo JI, Tuma RF, The combination of selective inhibition of the cannabinoid CB1 receptor and activation of the cannabinoid CB2 receptor yields improved attenuation of motor and autonomic deficits in a mouse model of spinal cord injury. Clin Neurosurg 56:(84-92) 2009.

Loftus CM, Levene HB:  Carotid Endarterectomy. In Basso A, Goland J (eds). Neurocirugia, aspectos clinicos y quirurgicos.  Buenos Aires, Editorial Corpus Argentina, 2008.

Loftus CM (ed.):  Neurosurgical Emergencies, 2nd edition.  (Chinese translation).  New York, AANS/Thieme Medical Publishers, 2009.

Loftus CM:  Carotid Artery Surgery: Principles and Technique. 2nd edition.  (Chinese Translation). Beijing, People’s Military Medical Press, 2009.

Fleck JD, Biller J, Harbaugh RE, Loftus CM: Carotid Occlusive Disease: Natural History and Medical Management. In Winn HR (ed.):  Youmans’ Neurological Surgery, Seventh Edition, Philadelphia, W.B. Saunders 2010.

Heller JE, Loftus CM:  Carotid Endarterectomy.  In Abdulrauf, SI (ed.): Cerebral Revascularization. Techniques in Extracranial-to-Intracranial Bypass Surgery, Philadelphia, Elsevier, 2010.

Bookland M, Loftus CM: Surgical Management of Extracranial Carotid Artery Disease. In Schmidek HH, Roberts DW (eds.): Operative Neurosurgical Techniques, 6th edition.  Philadelphia, Saunders/Elsevier, 2010.

Bookland M, Loftus CM:  Carotid Endarterectomy. In Kalangu KN, Kato Y, Dechambenoit G, (eds.): Essential Practice of Neurosurgery. Nagoya, Access Publishing, 2010, pp. 628-641.

Bookland M, Loftus CM:  Carotid Endarterectomy versus Carotid Stenting 2010.  In Al-Mefty O, Origitano TC, Harley HL: Controversies in Neurosurgery.  (in press 2010).

Smith GA, Hakma Z, Loftus CM: Interventions for Ischemic Stroke.  In Ferro J, Biller J (eds.), Evidence-Based Management of Stroke. Shropshire, UK, TFM Publishing, (in press 2010).

Sukul V, Jette T, Loftus CM: Optimal approaches to skin preparation prior to neurosurgery.  In: US Neurology, Volume 6, Number 2.  London, Touch Briefings, 2010 (in press).

Jallo JI, Loftus CM (eds.):  Neurotrauma and Critical Care of the Brain. (Chinese Translation).  Shanghai, Shanghai Scientific and Technical Pubishers, 2013.

Sukul V, Bookland M, Loftus CM: Tips and Secrets for Carotid Reconstruction. In: Proceedings of the 13th Asian-Australasian Congress of Neurological Surgeons - AACNS (December 1-4, 2011, Taipei, Taiwan). Medimond – Monduzzi Editore International Proceedings Division, Bologna (Italy), 2012.

Bookland M, Loftus CM: Carotid Endarterectomy. In Spetzler RF, Kalani MY, Nakaji P (eds.): Neurovascular Surgery, 2nd Edition. New York, Thieme Medical Publishers (in press 2012).

Ramani PS, Park C-K, Loftus CM, Mizuno J, Bajamal AH, Osorio-Fonseca E, Patkar S:  Textbook of Surgical Management of Lumbar Disc Herniation. Mumbai, Jaypee Brothers Publishing, 2013.

Jallo JI, Loftus CM (eds.):  Neurotrauma and Critical Care of the Brain. (Spanish Translation).  Buenos Aires, Ediciones Journal, 2013.

Kim R, Ray P, Loftus CM, Kim BS:  Minimally invasive lumbar microdiscectomy.  In Ramani PS, Park C-K, Loftus CM, Mizuno J, Bajamal AH, Osorio-Fonseca E, Patkar S:  Textbook of Surgical Management of Lumbar Disc Herniation. Mumbai, Jaypee Brothers Publishing, 2013, pp. 192-198.

Bookland M, Loftus CM: Extracranial Carotid Disease: Evaluation and Management. In Lanzer P (Ed.) PanVascular Medicine, 2nd edition, vol.x, pp xx–xxx. Springer Heidelberg New York Dordrecht London.

Loftus CM, Biller J, Baron EF (eds.):  Intraoperative Neuromonitoring,  New York, McGraw-Hill, 2013.

Braca JA, Bookland MJ, Heiferman DM, Loftus CM:  Chapter 74 -  Indications for Carotid Endarterectomy in Patients with Asymptomatic and Symptomatic Carotid Stenosis.  In Grotta J (ed): Stroke: Pathophysiology, Diagnosis, and Management, 6th edition, Elsevier 2014.

Ackerman PD, Loftus CM: Chapter 40 - Carotid Endarterectomy: Neurological Surgery Perspective.  In Sekhar L, Fessler RG (eds.):  Atlas of Neurosurgical Techniques – Cranial Surgery, 2nd edition.  New York, Thieme Medical Publishers, 2014 (in press).

Ackerman PD, Cooke J, Harbaugh RE, Loftus CM: Chapter 349 - Carotid Occlusive Disease: Natural History and Medical Management. In Winn HR (ed.):  Youmans’ Neurological Surgery, Eighth Edition, Philadelphia, Elsevier 2015 (in press).

Ackerman PD, Loftus CM. Symptomatic Extracranial Carotid Artery Stenosis. In Harbaugh RE, Berger MS, Couldwell WT, and Shaffrey C (eds.): Neurosurgery Knowledge Update. AANS and Thieme Medical Publishers. [Accepted 2014; In Press]

Schneck MJ, Ackerman PD, Loftus CM. Choosing the right patients for carotid artery procedural interventions. In: Biller J (ed.): Common Pitfalls in Cerebrovascular Disease: Case-Based Learning. New York, NY: Cambridge University Press. [Accepted 2014; In Press]

Loftus CM (ed.): Anticoagulation and Hemostasis in Neurosurgery. New York, Springer, June 2016.

Heiferman D, Wemhoff M, Loftus CM: “Asymptomatic extracranial carotid artery stenosis”. In Rangel-Castilla L, Nakaji P, Siddiqui A, Spetzler RF, and Levy E: Decision Making in Cerebrovascular Diseases. New York, Taylor and Francis, 2016 (in press).

Spencer DA, Ackerman PD, Iqbal IQ, Loftus CM: Special considerations of antiplatelet therapy, anticoagulation and the need for reversal in neurosurgical emergencies. In Loftus CM (ed.) Neurosurgical Emergencies 3rd edition. New York, Thieme, 2016 (in press).

Heiferman DM, Loftus CM: Management of Cerebellar Hematomas and Infarcts. In Caplan L (ed.): Primer on Cerebrovascular Diseases, Second Edition, New York, Elsevier, 2016 (in press).

Mendelow AD, Loftus CM: Spontaneous Intracerebral Hemorrhage. In Loftus CM (ed.) Neurosurgical Emergencies 3rd edition. New York, Thieme, 2016 (in press).

Schneck MJ, Loftus CM: Surgical Intervention for Acute Ischemic Stroke. In Loftus CM (ed.) Neurosurgical Emergencies 3rd edition. New York, Thieme, 2016 (in press).

Book and Article Reviews
Loftus CM: Review of Cerebral Vascular Disease in Children and Adolescents (Current Neurosurgical Practice Series), Eds. M.S.B. Edwards and H.J. Hoffmann, Williams & Wilkins, Baltimore, 1989 pp 480.  Neurosurgery, 25(3):476,1989.

Loftus CM: Review of Intracranial Aneurysm Surgery: Techniques. Eds. D.S. Samson and H.H. Batjer, Futura Publishing Company, Inc., Mount Kisco, NY, 1990 pp 248.  Neurosurgery, 29(2):316, 1991.

Loftus CM:  Editorial comment on "Cognitive outcome and quality of life one year after subarachnoid haemorrhage".  Neurosurgery 24(3):367, 1989.

Loftus CM:  Editorial comment on "Intracranial extradural pressure monitoring after direct operation on ruptured cerebral aneurysms".  Neurosurgery 24(6):883, 1989.

Loftus CM:  Editorial comment on “Correlation of contralateral stenosis and intraoperative electroencephalogram change with risk of stroke during carotid endarterectomy.  Neurosurgery 30: 194, 1992.

Loftus CM:  Editorial comment on “Protein kinase C activity correlates with the growth rate of malignant gliomas: Part II.  Effects of glioma mitogens and modulators of protein kinase C.  Neurosurgery 31(4): 724, 1992.

Loftus CM:  Editorial comment on "Relation between protein kinase C and calmodulin systems in cerebrovascular contraction: Investigation of the pathogenesis of vasospasm after subarachnoid hemorrhage".  Neurosurgery 31(4):716, 1992.

Loftus CM:  Editorial comment on “Cerebral arterial diameters during changes in blood pressure and carbon dioxide during craniotomy.  Neurosurgery 32:741-742, 1993.

Loftus CM:  Editorial comment on “Spinal arterial aneurysm: Case report”.  Neurosurgery 33:130, 1993.

Loftus CM: Editorial comment on "Treatment of hypertensive cerebellar hemorrhage - Surgical or conservative management?  Neurosurgery 34:251, 1994.

Loftus CM:  Editorial comment on “Duplex accuracy compared with angiography in the Veterans Affairs Cooperative Studies trial for symptomatic carotid stenosis.  Neurosurgery 36:654, 1995.

Loftus CM:  Editorial comment on “ A randomized trial of intraoperative, intracisternal tissue plasminogen activator for the prevention of vasospasm.  Neurosurgery 37:177, 1995.

Loftus CM:  Editorial comment on "Early discharge after carotid endarterectomy".  Neurosurgery 37:224-225, 1995.

Loftus CM:  Editorial comment on “Factors leading to early reoccurrence of carotid plaque after carotid endarterectomy”. Surg Neurol 43:284, 1995.

Loftus CM:  Editorial comment on “Effect of mannitol on focal cerebral ischemia evaluated by somatosensory-evoked potentials and magnetic resonance imaging”.  Surg Neurol 44: 61, 1995.

Loftus CM:  Editorial comment on "Cost-effectiveness of carotid endarterectomy.  Neurosurgery 38:244, 1996.

Loftus CM:  Editorial comment on "Segments of the internal carotid artery: A new classification."  Neurosurgery 38:432, 1996.

Loftus CM:  Editorial comment on “Multiple cerebral arterial occlusions in a young patient with Sjogren’s syndrome: Case report.”  Neurosurgery 38:595, 1996.

Loftus CM:  Editorial comment on “Evaluation of time-dependent thresholds of cerebral blood flow and transit time during the acute stage of cerebral embolism: a retrospective study.  Surg Neurol 46:145-46, 1996.

Loftus CM:  Editorial comment on “Physiologic diagnosis and surgical treatment of recurrent limb shaking: Case report”.  Neurosurgery 39:611, 1996.

Loftus CM:  Editorial comment on “Complications due to saphenous vein patch graft after carotid endarterectomy.”  Neurosurgery 39:676, 1996.

Loftus CM: Review of Operative Neurosurgical Techniques,  Schmidek HH and Sweet  WH (eds.).  J Neurosurg 85:521-522, 1996.

Loftus CM:  Editorial comment on “Byron Stookey, “The Old Lion” -  an unsung giant of neurosurgery.  Neurosurgery 40:388, 1997.

Loftus CM:  Editorial comment on “Treatment of dissecting pseudoaneurysm of the cervical internal carotid artery using a wall stent and detachable coils:  Case report.  Neurosurgery 40:625-626, 1997.

Loftus CM:  Editorial comment on “Hemodynamic instability after carotid endarterectomy: risk factors and associations with operative complications”.  Neurosurgery 41:43, 1997.

Loftus CM:  Editorial comment on “Impairment of the modulatory role of nitric oxide on the endothelin-1-elicited contraction of cerebral arteries: A pathogenetic factor in cerebral vasospasm after subarachnoid hemorrhage?” Neurosurgery 41:252, 1997.

Loftus CM:  Editorial comment on “A review of stress ulcer prophylaxis in the neurosurgical intensive care unit.”  Neurosurgery 41: 426, 1977.

Loftus CM:  Editorial comment on “Detection of embolic signals during and after percutaneous transluminal angioplasty of subclavian and vertebral arteries using transcranial Doppler ultrasonography.”  Neurosurgery 41:540-541, 1997.

Loftus CM:  Editorial comment on “Carotid endarterectomy in the presence of a persistent hypoglossal artery: A case report.”  Neurosurgery 41:672, 1997.

Loftus CM:  Editorial comment on “Carotid endarterectomy closure using a vascular clip system”.  Neurosurgery 42:554, 1998.

Loftus CM:  Editorial comment on  “Intracranial aneurysms associated with aortitis syndrome: Case report and review of the literature”.  Neurosurgery 42: 160, 1998.

Loftus CM:  Editorial comment on “ Bilateral dissecting aneurysms of the vertebral arteries resulting in subarachnoid hemorrhage: Case report”.  Neurosurgery 42:165, 1998.

Loftus CM:  Editorial comment on “Endovascular treatment of carotid artery occlusion in progressive stroke syndromes: Technical note”.  Neurosurgery 42:191-192, 1998.

Loftus CM:  Editorial comment on “Preoperative volume expansion improves tolerance to carotid artery cross-clamping during endarterectomy”.  Neurosurgery 43: 226, 1998.

Loftus CM:  Editorial comment on “Diagnosis and monitoring of cerebral hyperperfusion after carotid endarterectomy with single photon emission computed tomography: Case report.  Neurosurgery 43:  160-161, 1998.

Loftus CM:  Editorial comment on “Induced hypervolemia and inotropic support for acute cerebral arterial insufficiency: an underused therapy”.  Surg Neurol 49:54-56, 1998.

Loftus CM:  Editorial comment on “Failure of saphenous vein extracranial-intracranial bypass graft to protect against bilateral MCA ischemia after carotid occlusion.  Neurosurgery 45(2):367, 1999.

Loftus CM:  Editorial comment on “Influence of degree of carotid stenosis and collateral pathways on cerebral vasoreactivity, and effect of carotid endarterectomy”.  Neurosurgery 42: 995, 1998.

Loftus CM:  Editorial comment on “A newly developed shunt system for carotid surgeries. T-shaped silicone shunt tubes and clamping devices: Technical note.  Neurosurgery 42:1185, 1998.

Loftus CM:  Editorial comment on “Fibromuscular dysplasia of the internal carotid artery associated with alpha 1-antitrypsin deficiency”.  Neurosurgery 43:234, 1998.

Loftus CM:  Editorial comment on “Successful surgical removal of giant arteriovenous malformation in a patient with hemophilia”.  Neurosurgery 43:1462, 1998.

Loftus CM:  Editorial comment on “Long-term graft patency rates and clinical outcomes after revascularization for symptomatic traumatic ICA dissection”.  Neurosurgery 43:768, 1998.

Loftus CM:  Editorial comment on “Postoperative hypotension after carotid angioplasty and stenting”. Neurosurgery 44(6):1324, 1999.

Loftus CM:  Editorial comment on “Primary stenting of the extracranial carotid artery in a patient with multiple cervical dissections: Technical case report.  Neurosurgery 43(4):959, 1998.

Loftus CM:  Editorial comment on “Transverse cervical artery bypass pedicle for common carotid artery occlusion – new adjunct for revascularization of the internal carotid artery domain.  Neurosurgery 45(2):299, 1999.

Loftus CM:  Editorial comment on “Revascularization of occluded internal carotid arteries: The role of the vasa vasorum: Report of four cases.  Neurosurgery 45(3):634, 1999.

Loftus CM:  Editorial comment on “The safety and efficacy of fixed dosing heparin in carotid endarterectomy”.  Neurosurgery 45:442, 1999.

Loftus CM:  Editorial comment on “Anticoagulants in neurosurgical patients: A review”.  Neurosurgery 45(4): 838, 1999.

Loftus CM:  Editorial comment on “Clinical outcomes of high risk patients undergoing carotid endarterectomy using regional anesthesia.”  Neurosurgery 45(4):786, 1999.

Loftus CM:  Editorial comment on “Anterior thalamoperforating artery aneurysm associated with internal carotid artery occlusion: Case report.”  Neurosurgery 45(4):911, 1999.

Loftus CM:  Editorial comment on “Prevention of complications resulting from endovascular carotid sacrifice: A retrospective assessment.”  Neurosurgery 46(4):918, 2000.

Loftus CM:  Editorial comment on “Is there a potential role for hyoid bone compression in pathogenesis of carotid artery stenosis?”  Surgical Neurology 51:653, 1999.

Loftus CM:  Editorial comment on “Effect of carotid endarterectomy on chronic ocular ischemic syndrome due to internal carotid artery stenosis.  Neurosurgery 48(2):334, 2001.

Loftus CM:  Editorial comment on “Superficial siderosis associated with multiple cavernous malformations: A report of three cases.”  Neurosurgery 48(5):1152, 2001.

Loftus CM:  Editorial comment on “Mycotic aneurysm of the carotid bifurcation in the neck: Case presentation and review of the literature.”  Neurosurgery 48(5):1157, 2001.

Loftus CM:  Editorial comment on “Elevation of soluble ICAM-1 levels in symptomatic and asymptomatic carotid atherosclerosis.”  Neurosurgery 48(4):723, 2001.

Loftus CM:  Editorial comment on “Neurosurgical procedures in Jehovah’s Witnesses: An increased risk?”. Neurosurgery 49(2):274, 2001.

Loftus CM:  Editorial comment on “Operative Nuances: Carotid endarterectomy using regional anesthesia”.  Neurosurgery 49(3): 646, 2001.

Loftus CM:  Editorial comment on “Management of spontaneous cerebellar hematomas: A prospective treatment protocol.” Neurosurgery 49(6):1388, 2001.

Loftus CM:  Editorial comment on “Serum protein S100B levels correlate with subclinical neurocognitive decline following carotid endarterectomy.”  Neurosurgery 49 (5): 1084, 2001.

Loftus CM:  Editorial comment on “Shaking limb transient ischemic attacks: Unusual presentation of carotid artery occlusive disease: Report of two cases.  Neurosurgery 51(2):488, 2002.

Loftus CM:  Editorial comment on “Primary intracerebral hemorrhage in Izumo City, Japan: Incidence rates and outcome in relation to the site of hemorrhage. Neurosurgery 53 (6):1299, 2003.

Loftus CM:  Editorial comment on “The history of neurosurgery at Temple University”.  Neurosurgery 55(3):697, 2004.

Loftus CM:  Editorial comment on “Simulation of clipping position for cerebral aneurysms using three-dimensional computed tomography angiography”. Neurologia Medico-chirurgica (Tokyo) 44: 13, 2004.

Loftus CM:  Editorial comment on “Use of a large angioplasty balloon for predilation is a risk factor for embolic complications in protected carotid stenting”.  Neurologia Medico-Chirugica (Tokyo) 44(7):343, 2004.

Loftus CM:  Editorial comment on “Supratentorial dynamic computed tomography for the diagnosis of vertebrobasilar ischemic stroke”  Neurologia Medico-chirurgica (Tokyo): (in press).

Loftus CM:  Editorial comment on “Simulation of endovascular neurointervention using silicone models: Imaging and manipulation”. Neurologia Medico-chirurgica (Tokyo) 45: 572-573, 2005.

Baron EM, Loftus CM:  Editorial comment on “Predictors of outcome for surgery for compressive cervical myelopathy: Retrospective analysis and prospective study. Neurologia Medico-chirurgica (Tokyo) 46(5):238-239, 2006.

Baron EM, Loftus CM:  Commentary on Dynamic Computed Tomography Myelography for the Investigation of Cervical Disease. Neurol Med Chir (Tokyo) 46(4):215-216, 2006.

Loftus CM:  Editorial comment on “High resolution three dimensional magnetic resonance angiography and three dimensional spoiled gradient recalled imaging in the evaluation of neurovascular compression in patients with trigeminal neuralga: a double-blind pilot study.  Neurosurgery 58(4):674, 2006.

Weaver MW, Loftus CM:  Editorial comment on “Hyponatremia in the neurosurgical patient”.  Neurosurgery 59(2):229, 2006.

Loftus CM:  Book review, Handbook of Complex Percutanous Carotid Intervention, Surgical Neurology 68:474 (2007).

Levene HB, Loftus CM:  Editorial comment on “Clinical characteristics and surgical management for juxtafacet csts of the lumbar spine”.  Neurologia Medico-Chirurgica (Tokyo) 47(6):257, 2007.

Loftus CM:  Editorial comment on “Rebleeding after endovascular embolization of ruptured cerebral aneurysms”.  Neurologia Medico-Chirurgica (Tokyo) 47: 446-447, 2007.

Levene HB, Loftus CM:  Editorial comment on "Morphometry of the Cervical Vertebral Pedicles as a Guide for Transpedicular Screw Fixation".  Neurologia Medico-Chirurgica (Tokyo) 47(3):107-8, 2007. 

Jungreis CA, Loftus CM: Editorial comment on “ Thin-section diffusion-weighted imaging of the infratentorium in patients with acute cerebral ischemia without aopparent lesion on conventional diffusion-weighted imaging”. Neurologia Medico-Chirurgica (Tokyo) 48: 113, 2008.

Levene HB, Loftus CM:  Editorial comment on “Prediction of postoperative alignment in patients undergoing anterior cervical fusion using autologous vertebral bone grafting”. Neurologia Medico-Chirurgica (Tokyo) 48(5):207, 2008.

Levene HB, Loftus CM: Editorial comment on “Repair and regeneration of vertebral body after antero-lateral partial vertebrectomy using beta-tricalcium phosphate”. Neurologia Medico-Chirurgica (Tokyo) 48(8):342, 2008.

Kim BS, Loftus CM:  Editorial comment on “Long-term follow up in patients with cervical disk disease treated by cervical anterior fusion using titanium cage implants”. Neurologia Medico-Chirurgica (Tokyo) 48(10):446, 2008.

Heller J, Loftus CM:  Editorial comment on “Edaravone (MCI-186) scavenges reactive oxygen species and ameliorates tissue damage in the murine spinal cord injury model”. Neurologia Medico-Chirurgica (Tokyo) 48(12):545, 2008.

Ray P, Loftus CM: Editorial comment on “Anthropomorphic analysis of lumbar disc heriation”. Neurologia Medico-Chirurgica (Tokyo) 49(3):107, 2009.

Loftus CM: Editorial comment on “Urgent Open Embolectomy for Cardioembolic Cervical Internal Carotid Artery Occlusion”.  Neurosurgical Review (2010) 33:341-348.

Heller JE, Loftus CM: Editorial comment on: “Clinical Analysis of Spinal Cord Injury With or Without Cervical Ossification of the Posterior Longitudinal Ligament, Spondylosis, and Canal Stenosis in Elderly Head Injury Patients.” Neurologia Medico-Chirurgica (Tokyo) 50, 461-465, 2010.

Loftus CM: Editorial comment on: “Carotid Endarterectomy for Stenoses of Twisted Carotid Bifurcations”. World Neurosurgery 73:e21, 2010.

Heller JE, Loftus CM:  Editorial comment on “Two-Level Anterior Lumbar Interbody Fusion With Percutaneous Pedicle Screw Fixation: a Minimum 3-Year Follow-up Study”. Neurologia Medico-Chirurgica (Tokyo) 2010, in press.

Hassaneen W, Loftus CM:  Ediitorial comment on “Triple-Balloon Shunting for Carotid Endarterectomy: A Novel Intraluminal Shunt Designed to Preserve Internal and External Carotid Blood Flows”. Neurosurgery 2013 (in press).

Ackerman PD, Loftus CM: Commentary on: Microsurgical Interintimal Dissection in Carotid Endarterectomy by Ichinose et al. World Neurosurg 2013 (in press).

Loftus CM: Editorial comment on Ms. No. ANCH-D-15-01184R1   “Efficacy of early carotid endarterectomy for vulnerable plaque in common carotid artery”. Acta Neurochirurgica 2016 (in press).

Loftus CM: Editorial comment on Ms. No. ANCH-D-15-01212  “The importance of internal carotid artery occlusion tolerance test in carotid endarcterectomy under locoregional anesthesia.”  Acta Neurochirurgica 2016 (in press).

Loftus CM: Editorial comment on Ms. No. ANCH-D-15-01262 “Predictive Factors for Decompressive Hemicraniectomy in Malignant Middle Cerebral Artery Infarction.  Acta Neurochirurgica 2016 (in press).

Li DD, Loftus CM: Editorial comment on Ms. No. NSR-03-15-0074.R1 - Management of traumatic carotid artery dissection: initial experience of a single center.  Neurosurgical Review (Heidelberg) 2016 (in press).

Spencer DA, Loftus CM: Editorial comment on Ms. No. ANCH-D-15-01208R1 - Predictors of  aneurysmal rebleed before definitive surgical or endovascular management. Acta Neurochirurgica 2016 (in press).

Loftus CM: Editorial comment on ANCH-D-16-00145R1 - Detection of Carotid Artery Stenosis using Histological Specimens: A Comparison of CT angiography, Magnetic Resonance Angiography, Digital Subtraction Angiography and Doppler Ultrasonography. Acta Neurochirurgica 2016 (in press).

Loftus CM: Editorial comment on NEU-D-16-00098R1, titled "Analysis of Recurrent Stenosis After Carotid Endarterectomy Featuring Primary Plaque Calcification". Neurosurgery 2016 (in press).

Loftus CM: Editorial comment on ANCH-D-16-00955, titled "Simple classification of carotid bifurcation: is it possible to predict twisted carotid artery during carotid endarterectomy?" Acta Neurochirurgica 2016 (in press).

Loftus CM: Editorial comment on ANCH-D-15-01269R2 Perioperative stroke after carotid endarterectomy: etiology and implicationsActa Neurochirurgica 2016 (in press).

Loftus CM: Editorial comment on ANCH-D-16-01185 Causes of poor outcome in patients admitted in good grade subarachnoid haemorrhage. Acta Neurochirurgica 2016 (in press).

Abstracts
Loftus CM, Kvam DA, Copeland BR, Quest DO:  "Seizures in the immediate postoperative period", Scientific Program (p.127), American Association of Neurological Surgeons, Honolulu, HI, 1982.

Loftus CM, Nilaver G, Defendini R, Post KD, Bein­feld M: "Motilin related immunoreactivity in mam­malian adenohypophysis and human pituitary adenoma somatotrophs", Soc Neurosci Abstr 9:1015, 1983.

Loftus CM: "Treatment of myeloma of the spine", Scientific Program, The New York Orthopaedic Hospital Alumni Association 58th Annual Meeting, New York NY, 1984.

Correll JW, Loftus CM, Tatemichi TK, Nichols FT, Kupsky WJ, Mohr JP: "Recurrent symptomatic lesions at the site of previous carotid endarterectomy", Scien­tific Program, The American Academy of Neurological Surgery, Hot Springs, VA, 1984.

Loftus CM, Nilaver G, Beinfeld MC, Post KD: Motilin related immunoreactivity in mammalian adeno­hypophysis, human pituitary adenoma somatotrophs, and CSF of patients with pituitary adenomas. Scientific Program (p.299), American Association of Neurological Surgeons, Denver CO, 1986.

Loftus CM, Starr J, Bernstein DD, Yamada TT, Hitchon PW: Somatosensory evoked potentials in a model of cerebral ischemia. Scientific Program (p.104), Congress of Neurological Surgeons, New Orleans, LA 1986.

Loftus CM, Silvidi JA, Bernstein DD:  Pre-existing bypass preserves rCBF following acute stroke.  Stroke 18:291, 1987 (abstr).

Dyste GN, Hitchon PW, Loftus CM, Menezes AH:  Management of multiple brain abscesses.  Scientific Program (p. 180), American Association of Neurological Surgeons, Dallas, TX, 1987.

Loftus CM, Silvidi JA, Bernstein D:  Protective effect of pre-existing STA-MCA bypass on rCBF following acute stroke in dogs.  Scientific Program (p. 310), American Association of Neurological Surgeons, Dallas, TX, 1987.

Loftus CM, Bernstein D, Starr J:  Microsphere analysis of rCBF in a canine model of hemispheric ischemia.  Scientific Program (p. 326), American Association of Neurological Surgeons, Dallas, TX, 1987.

Loftus CM, Bernstein DD, Starr J:  Microsphere analysis of RCBF and SSEP measurements in a canine model of hemispheric ischemia.  Scientific Manuscripts, International Symposium on Surgery for Cerebral Stroke, Sendai, Japan, 1987, p. 196.

Loftus CM, Silvidi JA, Bernstein DD:  Effect of pre-existing STA-MCA bypass on rCBF and SSEP's following acute stroke in dogs.  Scientific Manuscripts, International Symposium on Surgery for Cerebral Stroke, Sendai, Japan, 1987, p. 190.

Loftus CM, Silvidi JA, Bernstein DD:  Effects of hypercapnia on rCBF following prophylactic and delayed experimental STA-MCA bypass.  J Cereb Blood Flow Metab 7:(suppl 1), S271, 1987 (abstr).

Silvidi JA, Loftus CM, Bernstein DD:  Effects of hypercapnia on rCBF following prophylactic and delayed experimental STA-MCA bypass. Scientific Manuscripts (p.199) Congress of Neurological Surgeons, Baltimore MD 1987.

Loftus CM, Biller J, Godersky JC, Adams HP, Edwards PS:  Carotid endarterectomy in symptomatic elderly patients.  Scientific Manuscripts (p.198) Congress of Neurological Surgeons, Baltimore MD 1987.

Loftus CM, Adams HP, Flamm EJ, Godersky JC, Beck DW:  Relationship of admitting CT to vasospasm in patients treated with nicardipine following aneurysmal subarachnoid hemorrhage.  Scientific Manuscripts (p.211) Congress of Neurological Surgeons, Baltimore MD 1987.

Beck DW, Adams HP, Flamm EJ, Godersky JC, Loftus CM:  The combination of aminocaproic acid and nicardipine in the treatment of aneurysmal subarachnoid hemorrhage.  Scientific Manuscripts (p.195) Congress of Neurological Surgeons, Baltimore MD 1987.

Loftus CM, Silvidi JA, Bernstein DD:  Effects of experimental cerebral revascularization on rCBF and hypercapneic reactivity.  Scientific Manuscripts, (p.18) American Academy of Neurological Surgery, San Antonio TX, 1987.

Loftus CM: Carotid endarterectomy in symptomatic elderly patients.  VII Panamerican Congress of Neurology, San Juan PR, 1987.

Loftus CM: Technical controversies in carotid artery surgery. VII Panamerican Congress of Neurology, San Juan PR, 1987.

Silvidi JA, Loftus CM, Bernstein DD: Doppler modified carotid artery shunt.  Stroke 19:139, 1988 (abstr).

Detwiler KN, Loftus CM, et al: Management of cervical spine injuries in patients with ankylosing spondylitis.  AANS/CNS Joint Section on Disorders of the Spine and Peripheral Nerves, Phoenix AZ 1988.

Mattos MA, Shamma AR, Rossi N, Meng RL, Godersky JC, Loftus CM, Corson JD: Recurrent carotid stenosis: The value of postoperative serial duplex scanning.  16th Annual Symposium on Vascular Surgery, Maui HI, April 1988.

Loftus CM, Silvidi JA, Hitchon PW, Beck DW, Godersky JC: Microvascular Doppler system for cerebrovascular surgery. Scientific Program (p. 281), American Association of Neurological Surgeons, Toronto ON, April 1988.

Silvidi JA, Loftus CM, Miller BV, Bernstein DD, Detwiler KN: Design and experimental validation of a Doppler-modified carotid artery shunt. Scientific Program (p. 306), American Association of Neurological Surgeons, Toronto ON, April 1988.

Silvidi JA, Loftus CM, Bernstein DD, Detwiler KN: Cerebral autoregulation following experimental STA-MCA bypass in normal and ischemic brain. Scientific Program (p. 305), American Association of Neurological Surgeons, Toronto ON, April 1988.

Loftus CM, Detwiler KN, Bernstein DD, Heistad DD: Development and validation of a new model of intracranial collateral circulation. Scientific Program (p. 259), American Association of Neurological Surgeons, Toronto ON, April 1988.

Beattie B, Biller J, Loftus CM, Godersky JC, Adams HP, Bruno A: Morbidity associated with carotid endarterectomy after recent nonhemorrhagic cerebral infarction.  American Academy of Neurology 1987.

Biller J, Bruno A, Adams HP, Godersky JC, Loftus CM, Mitchell V, Banwart K: A randomized trial of aspirin or heparin in hospitalized patients with recent transient ischemic attacks. American Academy of Neurology 1987.

Detwiler KN, Loftus CM,  Zhou J-G, Bern­stein DD:  Comparison of prophylactic and delayed canine STA-MCA bypass in preservation of cerebral autoregulation following stroke. Scientific Program, Ninth International Symposium on Microsurgery for Cerebral Ischemia, Detroit MI, 1988

Detwiler KN, Loftus CM, Silvidi JA, Bernstein DD: Sympathetic effects on prophylactic EC-IC bypass.  Scientific Program, Ninth International Symposium on Microsurgery for Cerebral Ischemia, Detroit MI, 1988

Loftus CM, Detwiler KN, Bernstein DD, Heistad DD: Development and validation of a new model of intracranial collateral circulation. Scientific Program, Ninth International Symposium on Microsurgery for Cerebral Ischemia, Detroit MI, 1988

Zhou JG, Todd MM, Warner DS, Loftus CM: The effects of nitrous oxide on cerebral ischemic thresholds.  9th World Congress of Anesthesiologists, Washington DC, 1988.

Greene GM, Loftus CM:  Collateral cerebral blood flow in response to cerebral vasodilators.  Stroke 20:133, 1989 (abstr).

Biller J, Bruno A, Neiman RF, Loftus CM, Yuh WTC, Marsh  EE, Adams HP: Superior Cerebellar Artery Territory Infarction.  American Academy of Neurology Annual Meeting, 1990.

Greene GM. Loftus CM: Effect of 2-Chloroadenosine on Cerebral Collateral Vessels.  Microsurgery for Cerebrovascular Disease Tenth International Symposium.  San Francisco, June, 1990.

Muhonen MG, Loftus CM, Sawin PD, Heistad DD: Intravascular pressure and regional cerebral blood flow in the canine collateral dependent zone during profound  hypotension.  University of Iowa College of Medicine Research Day, Iowa City, IA, April 1991.

Muhonen MG, Loftus CM, Sawin PD, Bernstein DD: L-nitro Arginine (L-NOARG) attenuates cerebral blood flow during hypotension.  International Conference on Stroke, Geneva, Switz. May, 1991.

Muhonen MG, Loftus CM, Sawin PD, Greene GM, Heistad DD: Correlation between intraluminal pressure and regional cerebral blood flow in the collateral dependent tissues.  Congress of Neurological Surgeons, Orlando, FL October, 1991.

Muhonen MG, Loftus CM, Heistad DD: The effects of L-nitro arginine and L-arginine on cerebral collateral blood flow and endothelium-dependent relaxation.  Congress of Neurological Surgeons, Orlando, FL, October, 1991.

Muhonen MG, Loftus CM:  Studies of L-NNA and L-Arginine on cerebral collateral blood flow and endothelium-dependent relaxation.  The American Academy of Neurological Surgery Meeting, Gleneden Beach, OR, October, 1991.

Muhonen MG, Greene GM, Heistad DD, Loftus CM: Mechanism of cerebral vascular "steal" phenomenon during hypercarbia and seizures.  17th International Joint Conference on Stroke and Cerebral Circulation, Phoenix, Arizona, January, 1992.

Muhonen MG, Greene GM, Heistad DD, Loftus CM:  Mechanism of cerebrovascular "steal" phenomenon during hypercarbia and seizures.  American Association of Neurological Surgeons, San Francisco, CA, 1992.

Muhonen MG, Greene GM, Heistad DD, Loftus CM: Mechanism of cerebral hyperemia during hypercarbia and seizures.  American Association of Neurological Surgeons, San Francisco, CA, April, 1992.

Muhonen MG, Greene GM, Heistad DD, Loftus CM: Mechanism of cerebral hyperemia during hypercarbia and seizures.  University of Iowa College of Medicine Research Day.  Iowa City, IA, April, 1992.

Muhonen MG, Greene GM, Heistad DD, Loftus CM: Inverse steal phenomenon during inhibition of nitric oxide synthesis.  Iowa/Minnesota Neurosurgical Research Day, Minneapolis, MN, June, 1992.

Loftus CM, Muhonen MG:  Mechanism of cerebral vascular "steal" phenomenon during hypercarbia and seizures.  The American Academy of Neurological Surgery Meeting, Naples, FL, October, 1992.

Muhonen MG, Loftus CM, Heistad DD: Augmentation of blood flow through cerebral collaterals by inhibition of nitric oxide synthase.  Congress of Neurological Surgeons, Wash D.C., November, 1992.

Heistad DD, Loftus CM, Muhonen MG; Microcirculatory consequences of collateral circulation during arterial occlusion: Implications for Penumbra.  Microcirculatory Stasis in the Brain, Tokyo, Japan, May, 1993.

Muhonen, MG, Loftus CM, Faraci FM, Heistad DD: Augmentation of blood flow through cerebral collaterals by inhibition of nitric oxide synthase.  Microcirculatory Stasis in the Brain, Tokyo, Japan, May 1993.

Loftus CM, Muhonen MG: The Effects of Serotonin (5-HT) and 5 HT and 5HT2 Antagonists on Blood Flow to Normal Brain and Collateral Dependent Tissue.  The American Academy of Neurological Surgery, Litchfield, Arizona, October 1993.

Gerdes JS, Muhonen MG, Loftus CM: Effect of Methiothepin and Ketanserin on Serotonin-Induced Reduction in Blood Flow to Collateral-Dependent.  Congress of Neurological Surgeons, Vancouver BC, October 1993.

Gerdes JS, Muhonen, MG, Loftus CM: Effect of Serotonin on Regional Cerebral Blood Flow to Normal Cerebrum and Collateral-Dependent Tissue.  Congress of Neurological Surgeons, Vancouver BC, October 1993.

Gerdes JS, Ryken TC, Schelper R, Loftus CM, Traynelis VC: Examination of the blood-cerebrospinal fluid barrier in a canine model.  Soc Neurosci Abstr 19(1): 691, 1993 (abstr).

Muhonen MG, Mazzochi CA, Gerdes JS, Loftus CM:  Responses of cerebral collateral vessels to inhibition of ATP-sensitive potassium channels with glibenclamide.  American Heart Association 67th Scientific Sessions, Dallas TX November 1994 (#2146, p.276).

Muhonen MG, Gerdes JS, Martin DG, Loftus CM, Heistad DD:  Effects of serotonin on normal and collateral-dependent cerebral blood flow.  Stroke 26:168, 1995 (abstr).

Loftus CM, Todd MM, Torner JC, Gelb A, Craen R, Schubert A, Mahla M:  Intraoperative hypothermic protection during aneurysm surgery:  A pilot clinical trial.  J Neurol Neurosurg Psychiatry 61:553, 1996.

Rubin MD, Sato Y, Traynelis VC, Loftus CM, Follett KA, Ogura Y:  In vivo dissection of known and suspected intracranial aneurysms using CT angiography.  Radiological Society of North America 1996.

Todd MM, Carras D, Hindman B, Loftus CM, Gelb A, Craen R, Schubert A, Ebrahim Z, Mahla M, Warner D, and the IHAST Study Group:  A randomized prospective pilot trial of mild hypothermia during intracranial aneurysm surgery.  Anesthesiology 85:A165, 1996.

Loftus CM, Robertson SC:  The role of neuronal NO in collateral and normal rCBF. Scientific Manuscripts, (p.14) The American Academy of Neurological Surgery,  White Sulphur Springs, W.Va., Sept. 1996.

Robertson SC, Mazzochi CA, Loftus CM:  Effects of MK-801 on collateral blood flow after middle cerebral artery occlusion.  Scientific Program (p.185), The Congress of Neurological Surgeons, Montreal PQ, October 1996.

Robertson SC, Mazzochi CA, Loftus CM:  Effects of NMDA receptor activation on collateral cerebral blood flow.   Soc Neurosci Abstr 1996.

Todd MM, Carras D, Hindman B, Loftus CM, Gelb A, Craen A, Schubert A, Ebrahim Z, Mahla M, Warner D:  A pilot trial of hypothermia during aneurysm surgery.  J Neurosurg Anesthesiol 8:323, 1996.

Robertson SC, Wetjen NM, Beer BJ, Loftus CM:  Pre and post-ischemic effects of MK-801 on regional cerebral blood flow.  J Neurosurg 86: 406A,  1997.

Robertson SC, Barua M, Brown P, Loftus CM:  Increased blood flow through cerebral collaterals by inhibition of neuronal nitric oxide synthase.  J Neurosurg 86: 405A-406A, 1997.

Wetjen NM, Robertson SC, Beer BS, Loftus CM:  Effects of hypothermia on regional and collateral-dependent blood flow in the ischemic brain.  J Neurosurg 86:  405A, 1997.

Wellman BJ, Loftus CM, Kresowik TF, Todd MM, Granner M, Sawin P:  The differences in electroencephalographic changes in awake versus anesthetized carotid endarterectomy patients.  J Neurosurg 86: 405A, 1997.

Beer SJ,  Wetjen NM, Loftus CM:  Outcome after aneurysmal SAH in the elderly based on surgical timing.  J Neurosurg 86: 398A-399A, 1997.

Loftus CM:  Carotid Endarterectomy: A Status Report. Scientific manuscripts (p.49) AANS/CNS Joint Section on Cerebrovascular Surgery Annual Meeting, Anaheim CA  February 1997.

Loftus CM:  Current indications for carotid endarterectomy.  Scientific manuscripts (3B-22) p. 78, 5th International Workshop on Cerebrovascular Surgery, Fukuoka, Japan, March 3, 1997.

Loftus CM:  The role of neuronal NO in collateral and normal rCBF. Scientific manuscripts (PC-28) p. 209, 5th International Workshop on Cerebrovascular Surgery, Fukuoka, Japan, March 3, 1997.

Robertson SC, Loftus CM:  The role of neuronal nitric oxide in the regulation of collateral and normal cerebral blood flow after middle cerebral artery occlusion.  Scientific manuscripts (p.32), American Association of Neurological Surgeons, Denver CO, April 1997.

Sato Y, Traynelis V, Loftus CM, Follett KA, Rubin MD:  In vivo dissection of cerebral aneurysms using CT angiography. Scientific manuscripts (p.33), American Association of Neurological Surgeons, Denver, CO, April 1997.

Wellman BJ, Sato Y, Loftus CM:  Impact of 3-D CT angiography on clinical decision making in aneurysm surgery.  Scientific manuscripts (p.76), American Association of Neurological Surgeons, Denver, CO, April 1997.

Robertson SC, Barua M, Brown P, Loftus CM:  Reduction of blood flow through cerebral collaterals by inhibition of neuronal nitric oxide synthase. .  J Cereb Blood Flow Metab 17: (suppl 1), S398, 1997.

Wetjen NM, Robertson SC, Beer B, Loftus CM:  Hypothermia selectively preserves collateral dependent flow in the ischemic brain.  J Cereb Blood Flow Metab 17: (suppl 1), S41, 1997.

Loftus CM:  Surgical technique of carotid endarterectomy with special emphasis on primary Hemashield patch angioplasty.  Clin Neurol and Neurosurg 99: (suppl. 1), S63, 1997.

Loftus CM, Robertson SC:  The role of neuronal NO in collateral and normal rCBF.  Clin Neurol and Neurosurg 99: (suppl. 1), S141, 1997.

Loftus CM:  Current indications for carotid endarterectomy: Results of cooperative trials.  Clin Neurol and Neurosurg 99: (suppl. 1), S197, 1997.

Robertson SC, Brown PB, Loftus CM:  Effects of etomidate administration on cerebral collateral flow. Neurosurgery 41(3):744, 1997.

Sato Y, Quets JP, Sickels WJ, Traynelis VC, Loftus CM, Follett KA:  Accuracy assessment of CT angiography for three-dimensional measurement of intracranial aneurysm.  Radiological Society of North America #163, Chicago IL, November 30, 1997.

Sato Y, Quets JP, Traynelis VC, Loftus CM:  Helical CT-angiography of the basilar artery aneurysm. Radiological Society of North America #164, Chicago IL, November 30, 1997.

Ghodsi AS, Loftus CM, Traynelis VC, Quets J, Sato Y:  Evaluation of basilar artery aneurysms by helical computerized tomography angiography.  J Neurosurg 88:182A, 1998.

Ghodsi AS, Traynelis VC, Loftus CM, Follett KA, Sato Y, Quets J, Sickles W:  Accuracy assessment of computerized tomography-angiography for 3-D measurement of intracranial aneurysm geometry.  J Neurosurg 88:202A, 1998.

Garell PC, Loftus CM:  Moyamoya disease in the midwestern United States.  Scientific manuscripts, p. 43, AANS Annual meeting, Philadelphia, PA, April 1998.

Loftus CM, Todd MM, Torner JA, Gelb A, Schubert A, Mahla M:  Pilot data and study design for IHAST - A randomized intraoperative hypothermia for aneurysm surgery trial.  Scientific manuscripts (p.79), Neurosurgical Society of America 51st Annual Meeting, Quebec City, PQ, May 16, 1998.

Wetjen NM, Garell PC, Traynelis VC, Loftus CM:  Nutritional management of patients with high grade subarachnoid hemorrhage. Neurosurgery 43(3):691, 1998.

Loftus CM:  Design and clinical characteristics of a newly developed carotid artery shunt.  Scientific Manuscripts (p. 74), International Society for Neurosurgical Technology and Instrument Inventors, Las Vegas NV, May 2, 1999.

Loftus CM, Hindman B, Todd MM:  IHAST 2 trial of intraoperative hypothermia in aneurysm surgery: Trial design and current status.  Scientific manuscripts (p. 115), Fourth Annual Meeting AANS/CNS Section on Cerebrovascular Surgery, Kona, HI.

Loftus CM:  Intraoperative hypothermia: The IHAST study.  Stroke: (in press), 2001.

Loftus CM:  IHAST 2 trial of intraoperative hypothermia in aneurysm surgery. Trial design and current status.  Scientific Program (p.8), Southern Neurosurgical Society Annual Meeting, Austin, TX, March 16, 2001.

Loftus CM: IHAST 2 trial of intraoperative hypothermia in aneurysm surgery. Trial design and current status.  Scientific Program (p.27), Neurosurgical Society of America 54th Annual Meeting, Amelia Island, FL, June 7, 2001.

Snell, BE, Tompkins P, Stevens FA, Loftus CM:  Continuous purine metabolite analysis by intracerebral microdialysis in spontaneously hypertensive rats with focal cerebral ischemia.  J Cereb Blood Flow Metab 21: (suppl.1), S471, 2001.

Snell BE, Tompkins P, Stevens FA, Loftus CM. Continuous Purine Metabolite Analysis by Intracerebral Microdialysis in Spontaneously Hypertensive Rats with Focal Cerebral Ischemia. Poster 197. Congress of Neurological Surgeons 51st Annual Meeting, San Diego, California, September 29-October 4, 2001.

Snell BE, Tompkins P, Stevens FA, Loftus CM. Time Course of Neurochemical Pathway Activation in Spontaneously Hypertensive Rats with Focal Cerebral Ischemia by Intracerebral Microdialysis, The Fifth Joint Meeting of the AANS/CNS Section on Cerebrovascular Surgery and the American Society of Interventional and Therapeutic Neuroradiology, Addison (Dallas), Texas, February 3-6, 2002. 

Snell BE, Tompkins P, Stevens FA, Lerner MR, Brackett DJ, Loftus CM. Analysis of Gene Expression Employing a cDNA Expression Array in the Rat Model of Reversible, Focal Cerebral Ischemia, The Fifth Joint Meeting of the AANS/CNS Section on Cerebrovascular Surgery and the American Society of Interventional and Therapeutic Neuroradiology, Addison (Dallas), Texas, February 3-6, 2002. 

Wienecke RW, Snell BE, Tompkins P, Stevens FA, Loftus CM. Changes in Energy-Related Metabolites Following Focal Cerebral Ischemia in Spontaneously Hypertensive Rats, 2002 Annual Meeting of the Southern Neurosurgical Society, Savannah, Georgia, March 6-9, 2002.  Poster Presentations 

Snell BE, Tompkins P, Stevens FA, Loftus CM. Intracerebral Microdialysis Analysis of Neurochemical Pathway Activation Time Course in Spontaneously Hypertensive Rats with Focal Cerebral Ischemia, 2002 Annual Meeting of the American Association of Neurological Surgeons, Chicago, Illinois, April 6-11, 2002. 

Snell BE, Tompkins P, Stevens FA, Lerner MR, Brackett DJ, Loftus CM. Analysis of Gene Expression Modulation with Focal Cerebral Ischemia in Spontaneously Hypertensive Rats Utilizing a cDNA Expression Array, 2002 Annual Meeting of the American Association of Neurological Surgeons, Chicago, Illinois, April 6-11, 2002. 

Tompkins P, Wienecke RJ, Stevens F, Loftus CM:  Analysis of lactate and pyruvate levels by intracerebral microdialysis in spontaneously hypertensive rats in response to focal cerebral ischemia. J Cereb Blood Flow Metab 23 (suppl 1):274, 2003.

Loftus CM, Tompkins P, Wienecke RJ, Snell BE, Stevens A:  Intracerebral lactate and pyruvate response to a two hour reversible middle cerebral artery occlusion. Poster Session, 2004 Annual Meeting of the American Association of Neurological Surgeons, Orlando Fl, May 2-6, 2004. . 

Loftus CM, Surdell D, Tompkins P: Cerebral Ischemia: Cerebrovascular and Neurochemical Responses. Scientific Program, 7th International Neurotrauma Symposium, Adelaide, Australia, 12-16 September 2004.

Donaldson K, Baron EM, Jallo J, Laske DW, Weaver MW, Loftus CM, Dominique D: Vertebral Body Replacement with the VBR Cage in the Setting of Metastatic Spinal Disease: The Temple Experience (2002-2005). AO Spine Tumor Symposium, Baltimore MD, October 27, 2005.

Todd M, Loftus CM, Hindman B, Torner J, Clarke W, Weeks J, IHAST Investigators: Brain swelling, surgical exposure and outcome following subarachnoid hemorrhage (Abstract). Stroke 38: 542, 2007.

Loftus CM, Hakma Z:  The differences between electroencephalographic and somatosensory changes in patients undergoing carotid endarterectomy.  Acta Neurochir (Wien) 2007: (suppl) CLXIX.

Donaldson K, Jallo J, Laske D, Baron E, Weaver MW, Loftus C, Dominique D:  Vertebral body replacement in the setting of metastatic spinal disease.  Acta Neurochir (Wien) 2007: (suppl) CVIII.

Loftus CM:  High-Risk carotid endarterectomy.  Neurologia Medico-Chirurgia (Tokyo) 47 (suppl.): LS04-1, 2007, p. 51.

Loftus CM:  Temple approach to cervical spine disease.  Neurologia Medico-Chirurgia (Tokyo) 47 (suppl.): 3B-JA-1, 2007, p.241.

Loftus CM:  CEA or CAS: Which is the best treatment?  Neurologia Medico-Chirurgia (Tokyo) 47 (suppl.): 3E-S20-SE, 2007, p. 248.

Hakma Z, Loftus CM: Intraoperative Monitoring During CEA. Poster Presentation AANS Annual Meeting 2009, San Diego CA.