Neurology

Justin Kwan, MD

Associate Professor, Neurology, Lewis Katz School of Medicine at Temple University

About me

Clinical Interests
  • ALS
  • Muscular dystrophy
  • GBS
  • CIDP
  • Myositis
  • Myasthenia gravis
  • Hereditary neuropathy
Education
  • MD, State University of New York at Buffalo, School of Medicine and Biomedical Sciences, Buffalo, NY
Training
  • Fellowship, Neuromuscular Disorders, Department of Neurology, Baylor College of Medicine, Houston, TX
  • Senior Clinical Fellow, EMG Section, NINDS, National Institute of Health, Bethesda, MD
  • Residency, Neurology, Department of Neurology, Baylor College of Medicine, Houston, TX
Board Certification
  • Neurology
  • Neuromuscular Medicine
  • Electrodiagnostic Medicine
  • Clinical Neuromuscular Pathology
Memberships
  • American Academy of Neurology
  • American Association of Neuromuscular and Electrodiagnostic Medicine
  • Peripheral Nerve Society
Awards and Honors
  • William Weiner Award for Patient Centered Care, 2014
  • Golden Hammer Award, Excellence in Clinical Neurology and Dedication to Resident Teaching, Devotion to Patient Care, 2014
  • F. James Boland Memorial Award for Contributions in ALS, 2008
  • Neurology Student Teaching Award, Baylor College of Medicine, 2002-2004
  • Morris and Sadie Stein Neuroanatomy Award, 2000
  • Alpha Omega Alpha, 1999
  • Dean’s Commendation for Academic Excellence, 1997-1999 
  • James A. Gibson Anatomical Society Award- Academic Achievements in Anatomical Sciences, 1997
  • Phi Beta Kappa, 1996
  • Golden Key National Honor Society, 1996
  • Academic Dean’s List, Cornell University, 1992-1996

Publications

Selected Publications

Iwata NK, Kwan JY, Danielian LE, Tovar Moll, F, Bayat, E, Floeter, MK. White matter alterations differ in primary lateral sclerosis and amyotrophic lateral sclerosis. Brain. 2011 Sep; 134(Pt 9):2642-55. PMID: 21798965.

Pierson TM, Adams D, Bonn F, Martinelli P, Cherukuri PF, Teer JK, Hansen NF, Cruz P, Mullikin JC, Blakesley RW, Golas G, Kwan JY, Sandler A, Fajardo KF, Markello T, Tifft C, Blackstone C, Rugarli EI, Langer T, Gahl W, Toro C. Whole-exome sequencing identifies homozygous AFG3L2 mutations in a spastic ataxia-neuropathy syndrome linked to mitochondrial m-AAA proteases. PLoS Genetics. 2011 Oct;7(10):e1002325. PMID: 22022284.

Kwan JY, Jeong SY, Van Gelderen P, Deng HX, Quezado MM, Danielian LE, Butman JA, Chen L, Bayat E, Russell JA, Siddique T, Duyn JH, Rouault TA, Floeter MK. Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: Correlating 7 tesla MRI and pathology.  PLoS One. 2012;7(4):e35241. PMID: 22529995.

Kwan JY, Meoded A, Danielian LE, Wu T, Floeter MK. Structural imaging differences and longitudinal changes in primary lateral sclerosis and amyotrophic lateral sclerosis. NeuroImage: Clinical. 2013; 2: 151-160. PMID: 24179768.

Manoli I, Kwan JY, Wang Q, Rushing EJ, Tsokos M, Arai AE, Burch WM, Dispenzieri A, McPherron AC, Gahl WA. Chronic myopathy due to immunoglobulin light chain amyloidosis. Mol Genet Metab. 2013 Apr; 108(4):249-54. PMID: 23465863.

Tazen S, Figueroa K, Kwan JY, Goldman J, Hunt A, Sampson J, Gutmann L, Pulst SM, Mitsumoto H, Kuo SH. Amyotrophic lateral sclerosis and spinocerebellar ataxia type 2 in a family with full CAG repeat expansions of ATXN2. JAMA Neurol. 2013 Oct;70(10):1302-4. PMID: 23959108.

Meoded A, Kwan JY, Peters TL, Huey ED, Danielian LE, Wiggs E, Morrisette A, Wu TX, Russell JW, Bayat E, Grafman J, Floeter MK. Imaging findings associated with cognitive performance in primary lateral sclerosis and amyotrophic lateral sclerosis. Dement Geriatr Cogn Dis Extra. 2013 Aug 16;3(1):233-50.  PMID: 24052798.

Markello T, Chen D, Kwan JY, Horkayne-Szakaly I, Morrison A, Simakova O, Maric I, Lozier J, Cullinane AR, Kilo T, Meister L, Pakzad K, Bone W, Chainani S, Lee E, Links A, Boerkoel C, Fischer R, Toro C, White JG, Gahl WA, Gunay-Aygun M. York platelet syndrome is a CRAC channelopathy due to gain-of-function mutations in STIM1. Mol Genet Metab. 2014 Dec 24. pii: S1096-7192(14)00700-8.  PMID: 25577287.

Zilliox LA, Chandrasekaran K, Kwan JY, Russell JW.  Diabetes and Cognitive Impairment.  Curr Diab Rep. 2016 Sep;16(9):87.  PMID: 27491830.

Floeter MK, Bageac DV, Danielian LE, Braun LE, Traynor BJ, Kwan JY.  Longitudinal imaging in C9orf72 mutation carriers: relationship to phenotype. NeuroImage:Clin. 2016 Oct 22;12:1035-1043.  PMID: 27995069.

Cardenas AM, Sarlls JE, Kwan JY, Bageac D, Gala ZS, Danielian LE, Ray-Chaudhury A, Wang HW, Miller KL, Foxley S, Jbabdi S, Welsh RC, Floeter MK. Pathology of callosal damage in ALS: An ex-vivo, 7 T diffusion tensor MRI study. Neuroimage Clin. 2017 Apr 30;15:200-208.  PMID: 28529876.